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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN6
All Species:
26.97
Human Site:
Y717
Identified Species:
45.64
UniProt:
P51797
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51797
NP_001277.1
869
97217
Y717
L
E
R
R
Y
T
P
Y
P
N
L
Y
P
D
Q
Chimpanzee
Pan troglodytes
XP_514393
802
89426
D656
P
Y
P
N
L
Y
P
D
Q
S
P
S
E
D
W
Rhesus Macaque
Macaca mulatta
XP_001104721
869
97094
Y717
L
E
R
R
Y
T
P
Y
P
N
L
Y
P
D
Q
Dog
Lupus familis
XP_535404
889
99260
Y737
L
E
R
R
Y
T
P
Y
P
N
L
Y
P
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35454
870
96962
Y718
L
E
R
R
Y
T
P
Y
P
N
L
Y
P
D
Q
Rat
Rattus norvegicus
P51799
803
88712
N657
S
D
T
A
S
N
H
N
G
F
P
V
V
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516296
878
97865
Y726
L
E
R
R
Y
T
P
Y
P
N
L
Y
P
D
Q
Chicken
Gallus gallus
XP_417644
868
97172
Y716
L
E
R
R
Y
T
P
Y
P
N
L
Y
P
D
Q
Frog
Xenopus laevis
Q9W701
689
76782
D543
R
I
R
S
R
D
I
D
S
Y
K
V
N
T
E
Zebra Danio
Brachydanio rerio
XP_696527
863
96883
Y711
L
E
R
R
H
A
P
Y
P
N
L
Y
P
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
P657
G
F
P
V
V
D
P
P
S
S
D
E
I
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193438
761
83935
L615
G
V
P
Q
T
N
E
L
S
V
T
S
G
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
L646
R
S
H
L
L
V
L
L
Q
S
K
V
D
F
Q
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
E633
T
K
D
E
D
K
F
E
K
E
K
R
C
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
99.4
93.3
N.A.
96.7
40.8
N.A.
81.3
93.2
22.7
82.6
N.A.
N.A.
37.9
N.A.
49.8
Protein Similarity:
100
92.2
99.8
95.1
N.A.
98.7
58
N.A.
85.3
97.8
39.1
90.7
N.A.
N.A.
57.3
N.A.
64.6
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
100
100
6.6
86.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
100
100
13.3
93.3
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
8
0
8
15
0
15
0
0
8
0
8
58
8
% D
% Glu:
0
50
0
8
0
0
8
8
0
8
0
8
8
15
8
% E
% Phe:
0
8
0
0
0
0
8
0
0
8
0
0
0
8
0
% F
% Gly:
15
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% G
% His:
0
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
0
0
8
8
8
% I
% Lys:
0
8
0
0
0
8
0
0
8
0
22
0
0
0
0
% K
% Leu:
50
0
0
8
15
0
8
15
0
0
50
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
15
0
8
0
50
0
0
8
0
0
% N
% Pro:
8
0
22
0
0
0
65
8
50
0
15
0
50
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
15
0
0
0
0
0
58
% Q
% Arg:
15
0
58
50
8
0
0
0
0
0
0
8
0
8
8
% R
% Ser:
8
8
0
8
8
0
0
0
22
22
0
15
0
0
0
% S
% Thr:
8
0
8
0
8
43
0
0
0
0
8
0
0
8
0
% T
% Val:
0
8
0
8
8
8
0
0
0
8
0
22
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
0
0
43
8
0
50
0
8
0
50
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _